(C) 2012 Elsevier Ltd All rights reserved “
“Background: Th

(C) 2012 Elsevier Ltd. All rights reserved.”
“Background: The late cardiotoxic effects of anthracycline chemotherapy influence morbidity and mortality in the growing population of childhood cancer survivors. Even with lower anthracycline doses, evidence of adverse cardiac remodeling and reduced exercise capacity exist. IPI-549 order We aim to examine the relationship between cardiac structure, function and cardiovascular magnetic resonance (CMR) tissue characteristics with chemotherapy dose and exercise capacity in childhood cancer survivors.

Methods:

Thirty patients (15 +/- 3 years), at least 2 years following anthracycline treatment, underwent CMR, echocardiography, and cardiopulmonary exercise testing (peak VO2). CMR measured ventricular function, mass, T-1 and T-2 values, and myocardial extracellular volume fraction, ECV, a measure of diffuse fibrosis based on changes in myocardial T-1 values pre- and post-gadolinium. Cardiac function was also assessed with conventional and speckle tracking echocardiography.

Results:

Patients had normal LVEF (59 +/- 7%) but peak VO2 was 17% lower than age-predicted normal values and were correlated with anthracycline dose (r = -0.49). Increased ECV correlated with decreased mass/volume ratio (r = -0.64), decreased LV wall thickness/height Selleck AR-13324 ratio (r = -0.72), lower peak VO2(r = -0.52), and higher cumulative dose (r = 0.40). Echocardiographic measures of systolic and diastolic function were reduced compared to normal values (p < 0.01), but had no relation to ECV, peak VO2 or cumulative dose.

Conclusions: Myocardial T-1 and ECV were found to be early tissue markers of ventricular remodeling that may represent diffuse fibrosis in children with normal ejection fraction post anthracycline therapy, and are related to cumulative dose, exercise capacity and myocardial wall thinning.”
“Investigation of human embryo

implantation requires a non-disruptive Erastin means of studying the endometrium during the window of implantation. This stud), describes a novel approach of cytokine profiling in endometrial secretions. Endometrial secretions aspirated prior to embryo transfer from 210 women undergoing IVF or intracytoplasmic sperm injection were analysed by a multiplex immunoassay. Tell mediators [interleukin (IL)-1 beta, IL-6, IL-12, IL-18, tumour necrosis factor-alpha, macrophage migration inhibitory factor, eotaxin, monocyte chemotactic protein-1, interferon-gamma inducible protein-10, vascular endothelial, growth factor] were detectable in 90-100% of the samples. Heparin-binding epidermal growth factor, IL-5, IL-17, IL-10, Dickkopf homologue-1 and IL-15 were detected in 23-76%, whereas interferon-gamma was not detectable in any of the samples.

The odds ratio in stages 3 to 4 POP for hydronephrosis was 3 4 (9

The odds ratio in stages 3 to 4 POP for hydronephrosis was 3.4 (95% CI, 1.3 and 9.2). Hydronephrosis resolved in 95% of patients after they received treatment for POP.

The prevalence of hydronephrosis was 10.3% in patients with POP and patients with stages 3 to 4 POP were at particular higher risk. Hydronephrosis resolved in most of the patients after treatment for the prolapse.”
“P>Certain LCL161 supplier protein kinases have been shown to be crucial for plant cell signaling pathways associated with plant

immune responses. Here we identified a pepper (Capsicum annuum) receptor-like cytoplasmic protein kinase (RLCK) gene (CaPIK1) that is transcriptionally activated by infection with Xanthomonas campestris pv. vesicatoria (Xcv). Silencing of CaPIK1 in pepper plants confers enhanced susceptibility to Xcv infection. Salicylic acid-dependent defense responses are attenuated in the CaPIK1-silenced plants, including expression of salicylic acid-dependent genes, but not of Y-27632 Cell Cycle inhibitor a jasmonic acid-regulated gene. Induction of salicylic acid accumulation by Xcv infection is compromised in CaPIK1-silenced plants. The functional CaPIK1 protein not only autophosphorylates, but also phosphorylates

myelin basic protein. CaPIK1 exists in the cytoplasm and also localizes to the plasma membrane of plant cells via its N-terminus. Transient expression of CaPIK1 in pepper leaves leads to generation of reactive oxygen species (ROS), ultimately leading to hypersensitive cell death. Over-expression (OX) of CaPIK1 in Arabidopsis enhances the basal resistance to infection with Pseudomonas syringae pv. tomato and Hyaloperonospora

arabidopsidis, associated with elevated ROS bursts. Salicylic acid levels in CaPIK1-OX plants are higher than those in wild-type plants. Together, these results suggest that CaPIK1 modulates the signaling required for the salicylic acid-dependent defense response to pathogen infection.”
“A novel multilayer film based on gold nanoparticles (GNPs) and poly-(2,6-pyridinediamine)/multiwall carbon nanotubes composite Tariquidar (pPA/MWNTs) was exploited to develop a highly sensitive amperometric immunosensor for detecting human chorionic gonadotrophin (HCG). In this method, pPA/MWNTs composite was prepared by electro-polymerizing PA onto MWNTs modified electrode, and then GNPs were used as a linker to immobilize HCG antibody onto the pPA/MWNTs modified electrode. Cyclic voltammetry (CV) and scanning electron microscopy (SEM) were employed to characterize the assembly process and the performance of the immunosensor. Because of the synergistic effect of pPA and MWNTs, and the unique properties of GNPs, the obtained immunosensor exhibited a wide linear response to HCG in two range from 1.0 to 10.0 and 10.0 to 160.0 mIU mL(-1) with a relatively low detection limit of 0.3 mIU mL(-1) (S/N = 3).

05) were seen in final trials for Peg-Board accuracy (95 8% vs 79

05) were seen in final trials for Peg-Board accuracy (95.8% vs 79.0%), checkerboard deviation (4.8% vs 18.2%), and time (293 s vs 404 s), pattern-cutting time (257 s vs 399 s), and suture time (203 s vs 305 s). Time to previous session correlated with relative improvement in Peg-Board and pattern-cutting time (r = 0.300 and 0.277, P = 0.021 and 0.041), but no specific training interval was predictive of improvement. Residents found the course easy to attend (3.6), noted skills improvement (4.1), and found it useful

ALK targets (4.0).

Conclusion: Training in the weekend sessions improved performance of basic tasks on the robot. Training interval had a modest effect on some exercises and may be more important for difficult tasks. This training program is a useful supplement to resident training and would be easy to implement in most

programs.”
“Palsy of the abducens nerve is a neurological sign that has a wide range of causes due to the nerve’s extreme vulnerability. Need of immediate neuroimaging is a matter of debate in the literature, despite the risks of delaying the diagnosis of a skull base tumor.

The authors present 2 cases of skull base tumors in which the patients presented with recurrent and self-remitting episodes of sixth cranial SB431542 in vitro nerve palsy (SCNP). In both cases the clinical history exceeded 1 year. In a 17-year-old boy the diagnosis was made because of the onset of headache when the tumor reached a very large size. In a 12-year-old

boy the tumor was incidentally diagnosed when it was still small. In both patients surgery was performed and the postoperative course was uneventful. Pathological diagnosis of the tumor was consistent with that PLX3397 clinical trial of a chondrosarcoma in both cases.

Recurrent self-remitting episodes of SCNP, resembling transitory ischemic attacks, may be the presenting sign of a skull base tumor due to the anatomical relationships of these lesions with the petroclival segment of the sixth cranial nerve. Physicians should promptly recommend neuroimaging studies if SCNP presents with this peculiar course.”
“Werner’s syndrome is an extremely rare genetic disorder of the autosomal recessive type, characterized by features suggesting premature aging in young adulthood. Because of the concomitant hypogonadism, pregnancy among patients with Werner’s syndrome occurs extremely rarely. We present a case of a successful outcome of pregnancy complicated by Werner’s syndrome in a 34-year-old primigravida. The reason for early delivery by caesarean section, at 34th week of pregnancy, was exacerbation of coronary symptoms, with early signs of cardiac insufficiency. A healthy female child was born in a good condition, with birth weight of 1950 g.”
“No definitive procedure for cleft repair has been identified yet as the gold standard.

10 min1, 0 11 min1, 0 44 min1 and 0 15 min1 corresponding to ener

10 min1, 0.11 min1, 0.44 min1 and 0.15 min1 corresponding to energy densities of 1E + 05 J L1, 1.3E + 05 J L1, 1.5E + 05 J L1 and 1.8E + 05 J L1, respectively. The kinetics of the deiodination reactions were more complex due to subsequent iodide oxidation. CONCLUSION: DBD is very effective as a pretreatment or advanced treatment method for increasing the recalcitrant chemical’s biodegradability and making subsequent biological treatment more efficient. (c) 2012 Society of Chemical Industry”
“Translocation from the cytosol to the nucleus is an essential step in phytochrome (phy) signal transduction. In the case of phytochrome A (phyA), this step occurs with the help Evofosfamide mw of FHY1 (far-red-elongated

hypocotyl 1), a specific transport protein. To investigate the components involved in phyA transport, we used a cell-free system that facilitates the controlled addition

of transport factors. For this purpose, we isolated nuclei from the unicellular green algae Acetabularia acetabulum. These nuclei are up to 100 mu m in diameter and allow easy detection of imported proteins. Experiments with isolated nuclei of Acetabularia showed Selonsertib that FHY1 is sufficient for phyA transport. The reconstituted system demonstrates all the characteristics of phytochrome transport in Arabidopsis thaliana. In addition, FHY1 was also actively exported from the nucleus, consistent with its role as a shuttle protein in plants. Therefore, we believe that isolated Acetabularia nuclei may be used as a general tool to study nuclear transport of plant proteins.”
“Promoting

long-term adherence to lifestyle modification and choice of antidiabetic agent with low hypoglycemia risk profile and positive weight profile could be the most effective strategy in achieving sustained glycemic control and in reducing comorbidities. From this perspective, vast interest has been generated by glucagon-like peptide-1 (GLP-1) receptor agonists and dipeptidyl peptidase-4 inhibitors (DPP-4i). In AP24534 supplier this review our ten-year clinical and laboratory experience by in vitro and in vivo studies is reported. Herein, we reviewed available data on the efficacy and safety profile of GLP-1 receptor agonists and DPP-4i. The introduction of incretin hormone-based therapies represents a novel therapeutic strategy, because these drugs not only improve glycemia with minimal risk of hypoglycemia but also have other extraglycemic beneficial effects. In clinical studies, both GLP-1 receptor agonists and DPP-4i, improve beta cell function indexes. All these agents showed trophic effects on beta-cell mass in animal studies. The use of these drugs is associated with positive or neucral effect on body weight and improvements in blood pressure, diabetic dyslipidemia, hepatic steazosis markets, and myocardial function. These effects have the potential to reduce the burden of cardiovascular disease, which is a major cause of mortality in patients with diabetes.

Moreover, we also studied

Moreover, we also studied HSP inhibitor whether the presence apoptotic bodies in fresh semen was related to the resistance of the stallion spermatozoa to being incubated at 37 degrees C or being frozen and thawed. Fresh equine semen was stained with fluorescent dyes such as M540 and Annexin-V. Active Caspase 3 was studied in fresh semen through Western blotting and immunofluorescence with a specific antibody. Sperm kinematics was assessed in fresh, incubated and thawed samples using computer-assisted semen analysis, and viability was evaluated with the LIVE/DEAD Sperm Viability Kit. Overall, our results demonstrate for the first time the presence of apoptotic

bodies in equine semen. The quantity of apoptotic bodies was highly variable among stallions and was positively correlated with Caspase 3 activity in fresh samples and negatively correlated with the viability and motility of stallion spermatozoa after the cryopreservation process.”
“Background. PD0332991 Although

previous research suggests women report more severe pain than men, evidence for sex-related differences in pain-related disability is conflicting. Also, the impact of psychological factors on sex differences in disability is uncertain.

Objective. The purpose of this study is to assess sex differences in pain-related disability and evaluate whether they are accounted for by psychological factors.

Methods. Analysis of baseline data from the Stepped Care for Affective disorders and Musculoskeletal Pain study. Participants included 241 male and 249 female primary care patients with moderately severe persistent

pain of the back, hip, or knee. Multivariable log-linear models were used to determine the association between sex and pain-related disability and whether sex differences persisted after adjustment for psychiatric comorbidity and potential psychological mediators.

Results. Compared with men, women reported worse pain intensity, greater pain-related interference with function, and more disability days due to pain. They also had worse depression, anxiety, and self-efficacy. Sex differences in pain interference with function and pain disability days remained significant in multivariable models. Depression, poor self-efficacy, and fear of reinjury were independently associated with Ipatasertib price disability in both men and women.

Conclusions. Women report greater pain-related disability than do men, even after controlling for depression, anxiety, and other psychological factors. Pain management strategies that target functional disability may be particularly important in the treatment of women with pain.”
“Objectives: The endovascular first approach has led to increasing complexity for surgical bypass especially in those patients without autogenous conduit. The use of vein interposed at the distal anastomosis has been reported to improve the results of prosthetic grafts.

The study

does not propose changing the current 39 weeks

The study

does not propose changing the current 39 weeks threshold for ERCD.”
“Chronic hepatitis increases the risk of hepatocellular carcinoma (HCC). To test whether circulating proteins reflect hepatic carcinogenesis, sera from patients and controls were albumin depleted, enriched for glycoproteins, digested with trypsin, and subjected to reverse phase chromatography and tandem mass spectrometry. Alpha-fetoprotein enhancer binding protein (AFPebp), a tumor suppressor, was repeatedly identified in sera from chronic HBV hepatitis patients. We independently identified and quantified AFPebp with a deuterated, phenylisocyanate-labeled synthetic peptide standard. Elevated AFPebp levels in sera from chronic HBV hepatitis patients decreased as cancer developed. These data Selleck Fedratinib suggest that rising AFPebp levels in chronic HBV hepatitis may be protective, while falling levels may contribute to HCC development.”
“Objectives: To assess whether labor length differs by week of gestation.

Methods: In this observational cross-sectional study, we compared duration of labor by gestational age (36+0 through 40+6 weeks) in primiparous singleton parturients with

vertex presentation. Data were acquired for a period of 24 months (2010-2011).

Results: In general, the rate of change in cervical dilatation decreased as gestational week at delivery advanced: 1.8 +/- 1.0 cm/h, 1.5 +/- selleck chemicals llc 0.9 cm/h, 1.3 +/- 0.8 cm/h, 1.6 +/- 1.5, and 1.3 +/- 1.0 cm/h at 36th, 37th, 38th, 39th and 40th gestational week, respectively (p = 0.040). Concurrently, the total labor duration (1st+2nd+3rd stages) increased as gestational age advanced: 423.6 +/- 180.9 min, 496.5 +/- 212.6 min, 545.9 +/- 247.1 min, 483.8 +/- 256.3 min, and 568.2 +/- 273.8 min at 36th, 37th, 38th, 39th and 40th gestational GPCR Compound Library price week, respectively (p = 0.013).

Conclusions: Gestational week of pregnancy

may alter the duration of labor, specifically, the length of labor increases as gestational week at delivery advances.”
“Objective: To investigate whether single nucleotide polymorphisms (SNPs) in the Mn-superoxide dismutase gene (SOD2) underlie the susceptibility to noise-induced hearing loss (NIHL).

Methods: Audiometric data from 2400 Chinese Han workers who exposed to occupational noise were analyzed. DNA samples were collected from the 10% most susceptible and the 10% most resistant individuals, and five SNPs (SOD2 rs2842980, rs5746136, rs2758331, rs4880 and rs5746092) were genotyped by Taqman SNP Genotyping Kits. The SNP main effects and interactions between noise exposure and SNP were analyzed using logistic regression. Haplotypes were analyzed by using Haploview software.

Results: The CT genotype of rs4880 (SOD2 V16A SNP) was associated with a higher risk of NIHL (covariates-adjusted OR, 2.18; 95% CI, 1.34-3.54, P = 0.002).

1038/jhh 2010 52; published online 27 May 2010″
“A series of

1038/jhh.2010.52; published online 27 May 2010″
“A series of conducting copolymers were synthesized by chemical oxidative polymerization of imidazole (Imi) and pyridine (Py) in acetonitrile medium at ambient temperature. The yield, solubility, and conductivity of the copolymers were measured by changing the Imi/Py molar ratio from 0/100 to 100/0. The as-prepared Imi/Py conducting copolymers were characterized by UV-Visible, FTIR, H-1-NMR, DSC, TGA, and XRD. The results suggest that the resulting copolymers were more easily soluble in

most of the organic solvents than in polyimidazole. The polymer obtained is a real copolymer containing imidazole and pyridine units, but the Imi content calculated on the basis of Go 6983 datasheet the proton NMR spectra is lower than feed Imi content. The thermostability of the Imi/Py copolymer increases with increasing Imi unit content. The copolymers show comparatively EPZ004777 purchase higher conductivity and higher thermal stability than the homopolymer polypyridine and are lower than those of polyimidazole. (C) 2011 Wiley Periodicals, Inc. J Appl Polym Sci, 2012″
“Elk (Cervus elaphus) have recently been established as domestic livestock derived from extant wild populations and may provide insights into changes in genetic variation during domestication. We compared genetic variation at 10 microsatellite DNA loci and the mitochondrial DNA D-loop in 2 herds of domestic elk in Alaska and Canada and wild elk

from 8 locations in western North America and Asia. Average individual heterozygosity was 0.55 in domestic elk and 0.47 in wild elk, average number of alleles per locus was 4.1 in domestic elk and 3.9 in wild elk, https://www.sellecn.cn/products/BIBF1120.html and 4 mitochondrial DNA haplotypes were observed in domestic elk and 3 in wild elk. Levels of genetic

variation were not significantly different among the domestic elk and wild elk we analyzed. Our results are consistent with other studies showing that genetic variation can be maintained in domestic and wild populations of elk and other deer with appropriate management.”
“We report a late-time “”fireworks-like”" particle emission from laser-produced graphite plasma during its evolution. Plasmas were produced using graphite targets excited with 1064 nm Nd: yttrium aluminum garnet (YAG) laser in vacuum. The time evolution of graphite plasma was investigated using fast gated imaging and visible emission spectroscopy. The emission dynamics of plasma is rapidly changing with time and the delayed firework-like emission from the graphite target followed a black-body curve. Our studies indicated that such firework-like emission is strongly depended on target material properties and explained due to material spallation caused by overheating the trapped gases through thermal diffusion along the layer structures of graphite. (C) 2011 American Institute of Physics. [doi:10.1063/1.3631789]“
“Metabolic syndrome, a cluster of risk factors that increase the risk of cardiovascular morbidity and mortality, is common in patients with hypertension.


“beta-cyclodextrin (CD)-based linear water-soluble polymne


“beta-cyclodextrin (CD)-based linear water-soluble polymners were synthesized in a controlled manner by a One-pot synthesis method. The synthesized water-soluble Polymer was covalently fixed Onto Cotton surfaces by a polycondensation reaction at controlled conditions. Grafting on cotton fibers transfers the cyclodextrin properties onto its surface. The grafting occurred

through the formation of a crosslink between hydroxyl groups of cotton and CID polymer. This was confimed using FTIR spectroscopy, DSC, tensile strength, computer color matching, and solvent fastness analysis. The tensile strength of modified fiber samples was unchanged as compared to that of unmodified fiber samples. The percentage of grafting depended Oil a number of parameters and specifically Entinostat cost on (i) temperature, (ii) time, Defactinib and (iii) pH of the reaction medium. Similarly,

under optimum conditions the weight increase on cotton fabric due to the grafting reaction could reach 10-15 wt %, The grafted fabric shows good dyeability and solvent fastness properties. (c) 2008 Wiley Periodicais, Inc. J Appl Polym Sci 111: 2056-2061, 2009″
“Background: Although research into the effects of cocaine has focused on the ventral striatum, recent reports have identified a significant role for the dorsal striatum. Given the importance of the dorsal striatum in motor control, the purpose of the present study was to investigate potential sensorimotor deficits among cocaine users and the functional basis of these deficits within the striatum.

Methods: Functional buy LY2835219 magnetic resonance imaging data were collected from 14 right-handed, non-treatment seeking chronic cocaine users and 14 age and gender matched controls during performance of two finger-sequencing paradigms that differentially activate the caudate (internally-guided) and the putamen (externally-guided) interleaved with blocks of rest. The total percent signal change in the dorsal striatum and the contribution of the left and right caudate and putamen were calculated

and compared across groups and tasks.

Results: Significant deficits in sensorimotor control were observed in cocaine users for both motor tasks, with the most severe impairments present during internally-guided movements. Cocaine users lacked the typical functional segregation observed in the dorsal striatum of the control subjects. The total percent signal change in the dorsal striatum was not significantly different between the groups, but cocaine users activated significantly less contralateral caudate and putamen for internally-guided versus externally-guided movements, respectively.

Conclusion: These data provide clear evidence that chronic cocaine users have significant motor performance deficits that are accompanied by disrupted processing within the dorsal striatum. These data Suggest the effects of cocaine extend beyond the confines of the motivational domains of the ventral striatum.

Conclusions: The proportion of drug-resistant TB increased during

Conclusions: The proportion of drug-resistant TB increased during 1997-2005 in Sinaloa. Major efforts are needed to prevent the further rise and spread of drug-resistant selleckchem and MDR TB. (C) 2011 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved.”
“The use of foamed plastics gains

more and more interest every day. Flexible poly(vinyl chloride) (PVC) foams have excellent mechanical properties and low price, thus their application is extensive. Foams are produced from plastisols, which are based on the suspension of the PVC resin in a plasticizer. Phthalates are the most used plasticizers in flexible PVC foam formation. In this study, we have studied the influence of the phthalate ester-type

plasticizers on the foaming process and the quality of the foams obtained from the corresponding plastisols. For the plastisols prepared with the nine phthalate plasticizers considered, we have studied and discussed the complex and extensional viscosities; the thermal behavior (DSC) including the decomposition of the chemical blowing agent, and the foam production by rotational molding. In addition, we have characterized the foams obtained by thermomechanical analysis, density, and bubble size distribution. As expected, clear correlations have been learn more obtained between the molecular weight and structure of the plasticizer with the rheological behavior of the plastisols. The knowledge of the gelation and fusion processes and evolution of the extensional viscosity of the plastisols combined with the study of the thermal decomposition of the blowing agent in each plastisol allows for better understanding of the complex dynamic behavior of these foaming systems. (C) 2011 Wiley Periodicals, Inc. J Appl Polym APR-246 Sci 121: 1495-1505,

2011″
“Atorvastatin calcium (ATC), an anti-lipid BCS class II drug, is marketed in crystalline and amorphous solid forms. The objective of this study was to perform solid state characterization of commercial crystalline and amorphous ATC drug samples available in the Indian market. Six samples each of crystalline and amorphous ATC were characterized using X-ray powder diffractometry (XRPD), differential scanning calorimetry (DSC), thermogravimetric analysis, Karl Fisher titrimetry, microscopy (hot stage microscopy, scanning electron microscopy), contact angle, and intrinsic dissolution rate (IDR). All crystalline ATC samples were found to be stable form I, however one sample possessed polymorphic impurity, evidenced in XRPD and DSC analysis. Amongst the amorphous ATC samples, XRPD demonstrated five samples to be amorphous ‘form 27′, while, one matched amorphous ‘form 23′. Thermal behavior of amorphous ATC samples was compared to amorphous ATC generated by melt quenching in DSC. ATC was found to be an excellent glass former with T(g)/T(m) of 0.95.

9812 (P < 0 0001) in the mouse

The h-L curves trac

9812 (P < 0.0001) in the mouse.

The h-L curves tracked the amplitudes and time courses of the faCaTs in cardiac muscles GSK3235025 purchase more accurately than m-E functions. Based on this

result, we suggest that the h-L time constant may be a more reliable index than the m-E time constant for evaluating the rate of CICR from the SR in myocardial Ca(2+) handling. The h-L approach may provide a more useful model for the study of CICR during the contraction process induced by anesthetic agents.”
“Interindividual variability in the response to drug therapy is due, in part, to genetic mechanisms which influence the expression of genes involved with drug metabolism and transport. Genetic elements and processes such as DNA methylation, histone deacetylation, transcription factors, DNA sequence variants, Selleck PX-478 and microRNAs (miRNAs) can impact at either the transcriptional or translational levels to modulate gene expression. Identification of such genetic regulators has greatly advanced in the last decade. Genome-wide analyses, using different types of approaches and methodologies, have uncovered many potential

regulators of the expression of drug metabolizing enzymes and transporters. However, confirming the function of these putative regulators is necessary and requires further work in the laboratory, using techniques which are still evolving. It also still remains to be seen whether these findings have clinical implications for drug therapy but the realization of personalized

medicine is a possible consequence of this research. (C) 2010 John Wiley & Sons, Inc. WIREs Syst Biol Med 2011 3 299-313 DOI: 10.1002/wsbm.125″
“Currently, there is an increasing commercial demand for nanoparticles due to their wide applicability in various markets, such as medicine, catalysis, electronics, chemistry and energy. In this report, a simple and eco-friendly chemical reaction for the synthesis of silver nanoparticles (AgNPs) from Artemisia Sotrastaurin nilagirica (Asteraceae) has been developed. Silver nitrate was used as the metal precursor and hydrazine hydrate as a reducing agent. Scanning electron microscopy (SEM) and energy-dispersive spectroscopy (EDX) were used to characterise the nanoparticles obtained from A. nilagirica. The morphology of the AgNPs was determined by SEM and the average diameter of the particles was determined as 70-90 nm. The EDX analysis of the nanoparticles dispersion, using a range of 2-4 keV. confirmed the presence of elemental silver, with no other impurity peaks detected. In addition, the characterised AgNPs has the potential for various medical and industrial applications. The results showed that microbial susceptibility to AgNPs is different for each microorganism. (C) 2012 Elsevier B.V. All rights reserved.”
“Late-preterm infants are known to have greater mortality and morbidity when compared with term infants during the neonatal period. Obstetric management plays a substantial role in influencing neonatal outcomes.