Results. The Z-score of BMI corresponding to obese was recorded in 54 (13.8%) analyzed pers The Nigelkirk dedication coefficient had been 0.34, 0.17, 0.11 and 0.10 c.u. correspondingly. Summary. The share of overweight and obesity towards the boost in the linear dimensions regarding the liver as well as the amount of the gallbladder, the forming of diffuse changes and excessive aerocolia in line with the ultrasound evaluation was 10-34%.To date, it was established that the in-patient’s genotype plays a substantial part when you look at the development of trehalase enzymopathy the level of enzyme activity reduces when the G→A allele replacement takes place when you look at the rs2276064 locus of this TREH gene. To evaluate the prevalence of trehalase deficiency, substantial population-based studies are essential. Clinical observations reveal that the decreased activity of bowel trehalase is more typical in the Arctic compared to European populations. The goal of this study was to analyze the frequency for the alleles and alternatives of trehalase gene (rs2276064 TREH) within the indigenous α-D-Glucose anhydrous small-numbered populations of Siberia plus the Russian asia. Material and methods. With the Infinium iSelect HD Personalized BeadChip biochip on the iScan platform and real time polymerase sequence response on a Bio-Rad CFX96 Touch amplifier, genotyping of 1068 DNA samples had been completed, of which 711 represent 10 cultural groups of the indigenous individuals of the North of Siberia additionally the asia of the Russian Federatoloid populations compared to Caucasoid teams. It had been hypothesized that, even though the initial A*TREH allele prevalence in Mongoloid groups had been averagely large, an adaptation to a low-sugar protein-lipid “high-latitude” diet resulted in a weaker control over the upkeep associated with the carriage for the ancestral G allele. Trehalose malabsorption needs unique interest of specialists in neuro-scientific nutrition, gastroenterology, public health, and health genetics doing work in high-latitude regions.The creation of specific meals methods effective at fixing body weight and influencing lipid metabolism is an urgent task at the present stage. The key option to develop such food methods is to alter product pages Oral antibiotics (lipid, necessary protein, carb, mineral, supplement, etc.). The purpose of the analysis would be to obtain and define a new meals source of a natural kind of chromium for the prevention of hyperlipidemia and obesity in the form of a complex with peptide fractions of fermentolysate proteins of the Mactra chinensis bivalve mollusk through the Far Eastern area. Material and methods. Smooth food areas of the Mactra chinensis bivalve mollusk from the Far Eastern area (the engine muscle and mantle) were used as things of research. Mollusk specimens were collected within the Amur Bay in Summer – September 2022. Biotechnological adjustment of soft structure proteins had been completed utilizing alkaline protease protozyme B aided by the after variables the timeframe associated with the procedure – 12 and 24 hours, pH – 7.0-7.2, heat 5erval fractions with molecular loads of 18.0-12.5 kDa. The minimal specific content of the trace factor had been founded for high-molecular fractions of 160-67 kDa and low-molecular fraction weighing lower than 1.4 kDa. Summary. Biotechnological customization of soft structure proteins of the Mactra chinensis bivalve mollusk through the Far Eastern region caused it to be possible to have a balanced amino acid composition fermentolysate with a top content of the no-cost biologically active amino acid taurine. Fortification associated with the gotten fermentolysate with chromium demonstrated high effectiveness of its binding to the amino acid and peptide matrices of this protein hydrolysate. The chromium complex with fermentolysate of proteins for the Mactra chinensis bivalve mollusk may be used as a food source of chromium and taurine, including as a practical ingredient in special food systems when it comes to prevention of hyperlipidemia and obesity.A number of important nourishment take part in the folate pattern, and its effectiveness is based on the adequate Biosafety protection consumption of these. In inclusion, polymorphic alternatives for the methylenetetrahydrofolate reductase (MTHFR), methionine synthase reductase (MTRR) and methionine synthase (MTR) genes affect a wide range of biochemical reactions of this folate pattern and may additionally be thought to be a risk element when it comes to development of lots of conditions. The purpose of this research was to learn the prevalence of those risk facets. Information and methods. The prevalence of polymorphisms of the folate cycle genetics C677T polymorphism of this MTHFR gene and A66G polymorphism regarding the MTRR gene in a random stratified (by sex and age) sample of this adult population of the Omsk region [n=139, 51 guys, 88 ladies, aged 18 to 75 many years, median age 37 (26; 48) years] ended up being examined. The recognition of polymorphisms ended up being completed because of the approach to allele-specific polymerase chain response with an electrophoretic detection scheme.