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Gut. Current Issues in Intestinal Microbiology 2003, 4:71–75.PubMed Authors’ contributions All authors were part of a project group, which continuously followed and discussed the progress of the experiments. AP designed and carried out the animal studies, performed the statistical analysis and drafted the manuscript. TRL and HF conceived of the study and participated in its design and coordination as well as in the preparation of the manuscript.

ALP carried out the in vitro fermentation study, PMHH carried out the haptoglobin determination, JBA performed PRKACG the fluorescent tagging of the Salmonella strain, RBS performed the immunocytostaining and flow cytometry, and MP contributed to feed design and statistical analysis. SJL and AO contributed significantly to the interpretation of data and the preparation of the manuscript. All authors read and approved the final manuscript.”
“Background Patients with cystic fibrosis (CF), an autosomal recessively inherited disease caused by a mutation in the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) gene, are particularly susceptible to pulmonary infections with Pseudomonas aeruginosa [1, 2]. Colonization of the airways of CF patients with P. aeruginosa results in higher morbidity and mortality LY2606368 molecular weight because of the faster decline of the lung function, especially from the chronic infection phase onwards [3–5]. Detection of colonization and infection by this pathogen as early as possible enables to postpone the chronic infective stage and eventually to achieve the eradication of P. aeruginosa through early treatment.