We apologize to the readers for any inconvenience the typos may h

We apologize to the readers for any inconvenience the typos may have caused. “

73, 35–48; January 12, 2012) When analyzing reads corresponding to mature miRNAs from our sequencing data, an unnecessary filter was used which filtered out 333 miRNAs and miRNA∗s that have 0 reads on both guide and passenger strands of their precursors in at least one library. Most of these miRNAs have very low reads numbers in our libraries and in total accounted for < 0.1% of reads that mapped to miRNA RG7204 cost precursors. This did not affect any of the major conclusions we have drawn from our experiments but did make certain numbers in the main text inaccurate and the data shown in Figures 3, 4, and S3 and in Tables S2–S6 incomplete. The Supplemental Information has been corrected online, and corrected versions of Figures 3 and 4, as well as descriptions of errors in the main text, appear below. Modified Text (corrected parts are underlined below): 1. Page 38. Last paragraph: For example, miR-143 was expressed at relatively high levels in both neocortex and cerebellum (ranking at 31 and 52, respectively, from highest to lowest, average normalized per million reads number > 10,000) but expressed

at relatively low levels in all the examined neuron types (ranking after 156, average normalized per million reads number < 1,000, pairwise fold-change > 18, p < 10−22) (Table S2). Modified Figures: Figure 3. In the heat map, we added SCR7 supplier rows for the miRNAs which were filtered out. The hierarchical clustering is not affected. Modified Supplemental Tables: Table S2. We added data for miRNAs which were filtered out. “
“In this issue, we honor the legacy of David Hubel and Torsten Wiesel, whose pioneering work transformed the field of visual neuroscience. From their early characterization of neuronal response properties in primary visual cortex to their analysis of how experience impacts the development of the visual system, the work of Hubel and Wiesel revealed fundamental insights into cortical

architecture, function, and plasticity. The collection of reviews over in this issue was inspired by the 50th anniversary of their landmark paper “Receptive fields, binocular interaction and functional architecture in the cat’s visual cortex,” published in the Journal of Physiology in 1962 ( Hubel and Wiesel, 1962). While the functional and organizational principles laid out in this paper certainly set the stage for a host of subsequent studies in the visual system, its reach has extended far beyond V1. It is a true “classic” in neuroscience and has served not only to guide work in the visual system but also to inspire any neuroscientist seeking to understand how the activity of individual neurons can give rise to perception and behavior. Figure 1.  David Hubel and Torsten Wiesel Given the far-reaching implications of their work, it is not possible to do full justice to Hubel and Wiesel with a limited selection of reviews.

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