707 miles). Sections are further divided into sixteen portions (1/16 of a section) and designated by an alpha code in the PLSS. If the alpha code is listed for a WCR, it can be located to ±142.25 meters (466.7 Ganetespib solubility dmso feet). The California Department of Pesticide Regulation (2000) provided a digital PLSS dataset for California that extends the PLSS through the old Spanish land grants (where the PLSS does not formally exist) so that the entire state is covered by PLSS sections. The state contains 158,678 PLSS sections in 4692 townships. A tool was written in Visual Basic programing language that reads the

PLSS information from each record in the Excel spreadsheets provided by DWR and plots the point onto a digital map. The point was located in the

center of a given section (or 1/16 of a section when an alpha code was provided). In addition to plotting the well on a digital map, the program attributed the point location with INCB024360 nmr the JPEG or TIFF hyperlink so that the WCR images could be viewed onscreen when the point was clicked. The images were stored on an internal server so that they could be accessed through a GIS application, an intranet website, or through a file browser. A system was needed to determine whether each WCR was domestic or some other use in order to assign the domestic population to only domestic wells. However, it was not practical to open and view all 700,000+ WCRs, so a spatially unbiased, randomized sampling system was designed to facilitate viewing a limited number of WCRs. The system, designed to run on a GIS server, randomly selected one WCR within a given township and displayed the images onscreen through a web-browser interface, collectively known as the “well-log viewer”. The analyst would then record what type of WCR they were viewing by examining the driller’s log details (domestic, Montelukast Sodium public

supply, irrigation, etc.), what type of owner (individual, corporation, etc.) and the date the well was drilled or destroyed. These WCRs were coded “accepted”. Depending on the number of wells within that township, the program would continue to display randomly selected WCRs to the analyst until either 10% of the WCRs, or a maximum of 10 were accepted within that township. If there were less than 50 WCRs in the township, the analyst continued to view randomly selected WCRs until 5 were accepted; if there were less than 5 WCRs total, all were viewed. A WCR did not count toward these goals and was considered “rejected” if the well was identified as being destroyed, it was a test or monitoring well, the WCR did not contain a driller’s log, or the image hyperlink was broken. If the analyst had viewed 100 WCRs and was not able to successfully code and accept at least 10 valid wells, the township was still considered completed. The analysts continued this process until all townships within the state were accounted for.