The reduction in tumor growth is well correlated with decreased
microvascular density of the tumor cells in treated mice. In conclusion, this study reveals that COR-D-induced mitochondrial dysfunction is responsible for the induction of apoptotic cell death.”
“BACKGROUND: Nitrogen removal using microbial fuel cells (MFCs) is of great interest owing to the potential benefits of bioenergy production. In this study, simultaneous nitrification and denitrification in dual-cathode MFCs was investigated.
RESULTS: The dual-cathode MFCs investigated were capable of generating electricity and removing nitrogen, influenced by operating methods, nitrogen loading rates and external resistance. Depending on the ammonium concentration in the anode chamber, 84-97% of the ammonium nitrogen was removed via nitrification in the aerobic cathode. The removals of nitrate and total nitrogen were relatively low PARP activity (similar to 50%) at the influent ammonium concentration of 80 mg NH(4)(+)-N L(-1), but were significantly improved to more than 90% at a lower ammonium input ( 40 and 20mg NH(4)(+)-N L(-1)). When the electrode couples were electrically connected for different purposes, with high power output from the anode/aerobic cathode and high current generation from the anode/anoxic cathode, nitrogen removal was also improved. An investigation of aeration suggested that factors other than carbon supply, possibly inefficient
reactor configuration, also limited the performance of the developed MFC.
CONCLUSION: The experimental results BEZ235 price demonstrated that the proposed pathway was feasible with effective nitrogen and organic removal. This study provided valuable information for the further development of a continuously operated dual-cathode selleck inhibitor MFC system. (C) 2011 Society of Chemical Industry”
“Objective-To characterize the clinical and clinicopathologic effects and
evaluate outcome associated with oleander toxicosis in New World camelids.
Design-Retrospective case series.
Animals-11 Ilamas and 1 alpaca.
Procedures-Medical records from a veterinary medical teaching hospital from January 1, 1995, to December 31, 2006, were reviewed. Records of all New World camelids that had detectable amounts of oleandrin in samples of serum, urine, or gastrointestinal fluid were included in the study. Descriptive statistics were used to evaluate the history, physical examination findings, clinicopathologic data, and outcome of affected camelids.
Results-11 llamas and 1 alpaca met the inclusion criteria of the study. Either oleander plants were present where the camelids resided (n = 7) or oleander plant material was identified in the hay fed to the camelids (5). One llama was dead on arrival at the hospital, and another was euthanized upon admission because of financial concerns. Of the 10 treated camelids, 9 had evidence of acute renal failure, 7 had gastrointestinal signs, and 4 had cardiac dysrhythmias on initial evaluation.